Telangiectatic Osteosarcoma

Background Osteosarcoma is a most common, highly malignant bone tumor affecting children and adolescents in their early ages but it may occur in late ages after an initial bone disease such as Paget Disease . There are two types of osteosarcoma primary osteosarcoma Secondary osteosarcoma Telangiectatic osteosarcoma. It is  least common variant of osteosarcoma. This tumor mainly occur in metaphyseal region within the medullary cavity of long bones. It is characterized by blood filled vascular spaces lined by osteoblast cells. These osteoblast seperated by fibrus septa which contain malignant cells , multinucleated joint cells […]

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Juvenile Ankylosing Spondylitis

Background Ankylosing Spondylitis is a rare chronic inflammatory autoimmune disorder affecting primarily sacroiliac joint and axial skeletal. Affecting males more than females with a ratio of 2:1. It is one of the diseases among Spondyloarthropathies, others include * Psoriatic Arthritis * Reactive Arthritis * Enteropathic Arthritis * Undifferentiated Spondyloarthropathies. There is another form of Ankylosing Spondylitis that is juvenile Ankylosing Spondylitis affecting children under 16 years of age. Clinical Presentation Morning Stiffness lasting more than 30 minutes. Insidious onset pain. onset in early age, before 40. Peripheral  Enthesitis and Arthritis. organ-specific extra-articular manifestation […]

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